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“Tumor” narrates a relationship that has turned sinister and damaging, but neither party acknowledges the downfall and ultimate damage. In an interview with The Seventh Hex, Allie X developed into the song’s message: "‘Tumor’ Xplores the relationship between you and another person to that of a grotesque neoplasm that you have been aware of but chosen to ignore. It was inspired by those TV specials on people with 50 pound tumours who, amazingly have chosen not to go to the doctors or get them removed.