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Fast-paced and breathy, “Tame” typifies the quiet-loud Pixies dynamic that gave rise to the grunge movement. Musically, the song is based around a basic three-chord progression with three-bar phrases, “as opposed to a more square 16-beat feel that you would hear in a typical pop song” Black Francis told Esquire: "The lyrics of the song are about college girls who lived in my neighborhood in Boston that I found obnoxious or whatever. Probably I found college people in that area obnoxious in general