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Marijuana Recreational (VERY Strong) 45 Minutes All the effects of that sticky-icky leaf, without the smoke! The main active chemical in marijuana is THC (delta-9-tetrahydrocannabinol). The membranes of certain nerve cells in the brain contain protein receptors that bind to THC. Once securely in place, THC kicks off a series of cellular reactions that ultimately lead to the high that users experience when they smoke marijuana. That is EXACLTLY what we tried to emulate with this dose