"21 Questions" is a song performed by rapper 50 Cent. Nate Dogg, who gives additional vocals, is featured on the chorus and outro. The song was written by 50 Cent, K. Risto, J. Cameron, and V. Cameron for 50 Cent's commercial debut album Get Rich or Die Tryin' (2003). Released in 2003 as the album's second single, it became his second number one song in the United States after "In Da Club". It reached number six in the UK Singles Chart while "In Da Club" was at #23, giving him the rare feat of having two singles in the Top 30 at the same time.

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